Unmet needs in CCA — 1 of 3

Diagnosis of CCA presents significant clinical challenges7,8,10

CCA is usually asymptomatic in its early stages, often resulting in late diagnosis when patients are already at an advanced stage7,10


of iCCA cases are diagnosed because of an incidental finding, owing to non-specific symptoms7,11


of patients with pCCA present with painless jaundice; 10% present with acute cholangitis5,10

Pie charts developed by Incyte, based on references 5,7,10,11.

Lack of absolute diagnostic criteria and low specificity of diagnostic modalities make diagnosis of CCA difficult7,8,10

Question mark icon

What are the symptoms of advanced CCA?